The proenzyme pepsinogen is secreted mainly from which of the following structures? A. Gastric glands of the stomach B. Acinar cells of the pancreas C. Epithelial cells of the duodenum D. Ductal cells of the pancreas
A
A. Gastric glands of the stomach. Pepsinogen is secreted mainly from the chief cells (also called zymogenic cells) of the gastric glands located in the stomach. Pepsinogen is then converted into pepsin by the acidic environment of the stomach, and pepsin plays a crucial role in protein digestion. The other structures mentioned, including the acinar cells and ductal cells of the pancreas and epithelial cells of the duodenum, secrete enzymes and other substances involved in digestion but not pepsinogen.
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