Unlocking the Mystery: why Intrinsic Factor is Vital for Vitamin B12 Absorption while Fat-soluble Vitamins Rely on a Different Pathway

Which of the following is required for absorption of the fat soluble vitamins contained A. Chymotrypsin B. Pancreatic amylase C. Pancreatic lipase D. Intrinsic factor E. Secretin

CAbsorption of the fat-soluble vitamins (A, D, E, and K) is diminished if there is a lack of pancreatic lipase. Lipase is required to produce monoglycerides that, in combination with bile salts, make it possible to bring the fat-soluble vitamins close to the mucosal cell surface for absorption

The correct answer is D. Intrinsic factor.

Intrinsic factor is required for the absorption of vitamin B12, which is a fat-soluble vitamin. Fat-soluble vitamins include vitamins A, D, E, and K. However, the absorption of vitamin A, D, E, and K is not dependent on intrinsic factor. Rather, these vitamins follow a different pathway for absorption compared to vitamin B12.

Chymotrypsin is a digestive enzyme that breaks down proteins, while pancreatic amylase breaks down carbohydrates. Pancreatic lipase is a digestive enzyme that breaks down fats. Secretin is a hormone that regulates the secretion of pancreatic juice. While these substances are important for digestion and absorption of various nutrients, they are not specifically required for the absorption of fat-soluble vitamins.

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