Peptide Bonds: The Chemistry Behind Protein Formation

Peptide bond

covalent bond joining amino acids in a protein (polypeptide)

A peptide bond is a covalent chemical bond that forms between two amino acids when the carboxyl group (-COOH) of one amino acid reacts with the amino group (-NH2) of another amino acid, releasing a molecule of water (H2O). The resulting bond between the two amino acids is called a peptide bond. The amino acids joined by peptide bonds form a linear chain called a polypeptide chain, which can then fold into a specific three-dimensional shape to form a protein.

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