cells are binded by “spot welds” or rivets between cell membranes- provide a reinforced structural unitEXAMPLE: cells of the outer skin layer
how do desmosomes connect cells?
Cells in the outer skin layer (epidermis) are held together by specialized structures called desmosomes. These are also known as “spot welds” or “rivets” as they anchor adjacent cells to each other like tiny staples.
Desmosomes are formed by transmembrane glycoproteins called cadherins, which span the cell membrane and interact with cadherins on neighboring cells. The cadherins are linked to intermediate filaments inside the cell, creating a strong connection that resists mechanical stress. This way, the cells in the outer skin layer can withstand the pressure and stretching that occurs during daily activities like bending, twisting, and rubbing.
Overall, desmosomes provide a reinforced structural unit that keeps the cells of the epidermis tightly together, forming a durable and protective barrier on the surface of the body.
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