The Role of Hippocampus in Forming Long-Term Memories: Insights from Studies of Amnesic Patients

studies involving amnesic people strongly suggest that

the biological basis of long-term memory involves the hippocampus

studies involving amnesic people strongly suggest that the hippocampus is a crucial component of the brain for forming and storing long-term memories. The most famous case study involving an amnesic patient is that of H.M. In the 1950s, H.M. underwent brain surgery to treat seizures, during which his hippocampus was removed. As a result, he was unable to form new long-term memories but was able to remember information from before the surgery. This led researchers to conclude that the hippocampus plays a critical role in forming and consolidating long-term memories. Studies of other amnesic patients have further supported this conclusion. For example, amnesic patients may be able to learn new skills or perform tasks without remembering having done them before, further indicating that the hippocampus is specifically involved in forming declarative memories, which are conscious memories of facts and events. Overall, studies of amnesic patients have provided important insights into the functioning of the brain and the specific regions involved in forming and storing memories.

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